- Catalog number9562-50
- Product nameADX-47273
- Size50 mg
- PriceAsk For Price
- DescriptionADX-47273 is a potent and selective mGluR5 receptor PAM (positive allosteric modulator), EC₅₀ = 0.17 μm, with no effect on other mGluR subtypes. ADX-47273 elevates extracellular signal-regulated kinase and cAMP-responsive element-binding protein phosphorylation in hippocampus and prefrontal cortex.
- CAS Number851881-60-2
- Structure AvailableYes
- Salt FormNo
- Molecular FormulaC₂₀H₁₇F₂N₃O₂
- Molecular Weight369.37
- Cell PermeableYes
- Purity≥98% by HPLC
- SolubilitiesDMSO (>30 mg/ml)
- HandlingProtect from air and light
- Tag LineA potent and selective mGluR5 receptor PAM (positive allosteric modulator)
- Storage Condition-20°C
- Shipping Conditiongel pack
- Shelf Life36 months
- PubChem CID11383075
- PubChem CID Link
- SMILESC1CC(CN(C1)C(=O)C2=CC=C(C=C2)F)C3=NC(=NO3)C4=CC=C(C=C4)F
- InChiInChI=1S/C20H17F2N3O2/c21-16-7-3-13(4-8-16)18-23-19(27-24-18)15-2-1-11-25(12-15)20(26)14-5-9-17(22)10-6-14/h3-10,15H,1-2,11-12H2/t15-/m0/s1
- InChi KeyVXQCCZHCFBHTTD-HNNXBMFYSA-N
- Data Sheet Link
- MSDS AvailableYes
- Gene targetADX-47273
- Gene symbolFDX1
- Short nameADX-47273